Highlights

GlycoMIP’s second annual summer school was held in the VT GlycoMIP facility June 13-17, 2022. A diverse group of 22 academic and industry scientists from 11 different universities and companies participated in the program.

RSVP is a training and professional development program for visiting graduate students and early career researchers to learn on-site at the 2DCC for extended periods.

The GlycoMIP User Facility at Virginia Tech supported the research of Dr. Brandon Jutras, an Assistant Professor in the Department of Biochemistry at Virginia Tech and frontier researcher in understanding, detecting and eradicating Lyme disease. Dr. Jutras has published high-impact article in Nature Microbiology revealing the glycan composition of the Lyme disease spirochaete Borrelia burgdorferi’s cell wall.

Here, PARADIM users from Harvard and Arizona State Universities and their collaborators searched for hydrogen across a wide range of superconducting and non-superconducting layered nickelate films, with different cation and dopant chemistry, structures, growth methods, reduction conditions, and crystalline quality.

Here, PARADIM’s development of real-time temperature control during cryogenic scanning transmission electron microscopy has enabled its users to image the CDW transition while altering temperature and electric field. Unsupervised machine learning is applied to cluster the five-dimensional, terabyte scale microscopy datasets, and demonstrates a one-to-one correlation between device resistance, CDW phase, and the material microstructure. The team shows that basal dislocations—which are ubiquitous in 2D materials—both nucleate and pin the CDW transition and locally alter the transition temperature (Tc) by nearly ~75 K. Further, the team shows that the dislocation density can be used to engineer device properties.

In this work, 177 alloy spots from a CL with varying composition and structure were studied. Bulk samples of (FeCoNi)1-x-yCrxAly were prepared and processed at PARADIM using unique capabilities of its ancillary synthesis facility, including oxygen free arc melting and water jet cutting capabilities to enable quantitative comparisons with the CL spots. Due to varying grain size and the grain boundary dissolution a one-to-one correlation could not be made useful between thin films and bulk.

Meet Gottfried and Ingeborg – fully automated oligosaccharide synthesizers (Glyconeers®) from GlycoUniverse. The Glyconeers® are complemented by a suite of preparative and analytical instruments housed in the MP's synthesis facility that release resin-bound glycans, deprotect, purify, and characterize them.

The GlycoMIP SURF program offers a unique path to reach and engage prospective graduate students. The existing FLSI SURF program offers GlycoMIP the opportunity to participate in an existing program that, for many years, has successfully introduced undergraduate students to graduate-level research. Through this partnership, GlycoMIP offers students a comprehensive experience, including professional development workshops, significant laboratory work, and one-on-one mentorship by a faculty member or research scientist.

GlycoMIP hosted its first Summer School, a virtual event. The event featured 15 instructors and offered content aligned with the GlycomMIP Facilities of synthesis, analysis and modeling services.

Here, PARADIM presents X-ray scattering and spectroscopy measurements on a series of NdNiO2+x samples, which reveal that the signatures of charge density wave order are absent in fully reduced, single-phase NdNiO2. The 3a0 superlattice peak instead originates from a partially reduced impurity phase where excess apical oxygens form ordered rows with three-unit-cell periodicity.