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Gyros Protein Technologies Prelude® X Peptide Synthesizer

The Prelude X system (Gyros Protein Technologies) enables users to synthesize novel peptides and related structures (peptoids and other solid-phase synthesized sequence specific materials) not available for commercial purchase, providing a lower cost solution for producing peptides with non-natural amino-acids, and supporting the synthesis of branching or cyclic peptides.
Multi-user accessibility is facilitated via 6 reaction stations, enabling different sequences, scales, and protocols on each reactor. Typical scales span 10 mg to 2 g of resin in 10- or 40-mL reaction vessels (RVs) with induction heating up to 90°C for each RV to accelerate difficult deprotections and couplings. Agitation is performed by nitrogen bubbling, oscillation mixing, or a combination of these. The Prelude X has also been pre-configured with a number of optimized methods for rapid peptide and peptoid synthesis.
The Prelude X is available to BioPACIFIC MIP users through the CNSI Biological Nanostructures Laboratory
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This website is maintained collaboratively by teams supported by the Materials Innovation Platform awards, independent of the NSF. Any opinions, findings, and conclusions or recommendations expressed on this website are those of the team(s) and do not necessarily reflect the views of the National Science Foundation or the participating institutions.