Matrix-assisted laser desorption/ionization mass spectrometry imaging, or MALDI-MSI, is used to study distribution of molecules in sections of material, both biological and synthetic. The MALDI-2 has a second laser that boosts the yield of ions at small pixel sizes. The unit also reduces ion suppression effects resulting in more molecular features that could be obtained previously.

The combination of MALDI-2 with ion mobility separation (IMS) capabilities permits a number of applications, ranging from the analysis of small molecules on an array to the analysis of glycans from human tissues.

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