Gyros Protein Technologies PreludeĀ® X Peptide Synthesizer

Instrumentation | Synthesis and Formulation

The Prelude X system (Gyros Protein Technologies) enables users to synthesize novel peptides and related structures (peptoids and other solid-phase synthesized sequence specific materials) not available for commercial purchase, providing a lower cost solution for producing peptides with non-natural amino-acids, and supporting the synthesis of branching or cyclic peptides.
Multi-user accessibility is facilitated via 6 reaction stations, enabling different sequences, scales, and protocols on each reactor. Typical scales span 10 mg to 2 g of resin in 10- or 40-mL reaction vessels (RVs) with induction heating up to 90°C for each RV to accelerate difficult deprotections and couplings. Agitation is performed by nitrogen bubbling, oscillation mixing, or a combination of these. The Prelude X has also been pre-configured with a number of optimized methods for rapid peptide and peptoid synthesis.
The Prelude X is available to BioPACIFIC MIP users through the CNSI Biological Nanostructures Laboratory
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National Science Foundation

Division of Materials Research

2415 Eisenhower Avenue

Alexandria, VA 22314

Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.