The field of glycomaterials has been slowed by the inability to automate the synthesis of oligosaccharides. These molecules are a challenge to produce due to the inherent structural similarities of carbohydrates and the need for stereospecific bond formation. As oligosaccharide synthesis is inherently repetitive with multiple sequential steps, automated oligosaccharide synthesis is necessary. Initially pioneered by Peter Seeberger, the Glyconeer® is the first commercial, fully automated oligosaccharide synthesizer. This instrument, in combination with commercially available building blocks, enables users to quickly and reproducibly synthesize an array of higher order oligosaccharides.


Features of the Glyconeer® include:
• Delivery of solvents and reagents via argon pressure
• Compatible with a wide range of chemistries and various solvent/reagents combinations
• Software designed to maximize simplicity while maintaining functionality
• Temperature controlled reaction vessels (-40 to +80 °C)
• On-line UV detection to monitor coupling efficiency
• Synthesis scale from 10-100 micromoles
• 64-position carousel for the delivery of monosaccharide building blocks
• Triple-jacketed glass reaction vessel
• Separate fraction and waste collection